Neutrophil proteinases and matrix degradation. The cell biology of pericellular proteolysis.


Neutrophil proteinases have the capacity to degrade almost every component of the extracellular matrix. In marked contrast to the wealth of available data about the structure and activity of these proteinases when they are free in solution, there has been relatively little information about the mechanisms by which neutrophils use and control their… (More)

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