Neutrophil margination and extravasation in sinusoids and venules of liver during endotoxin-induced injury.

@article{Chosay1997NeutrophilMA,
  title={Neutrophil margination and extravasation in sinusoids and venules of liver during endotoxin-induced injury.},
  author={John G. Chosay and N A Essani and Colin J. Dunn and Hartmut Jaeschke},
  journal={The American journal of physiology},
  year={1997},
  volume={272 5 Pt 1},
  pages={G1195-200}
}
Neutrophils contribute to liver damage during endotoxin shock. The objective of this investigation was to document where neutrophils localize in the hepatic vasculature and whether they migrate out of sinusoids or postsinusoidal venules. A well-characterized model of galactosamine and endotoxin shock and immunostaining for neutrophil-associated migration inhibition factor-related protein complex 8/14 S100 calcium-binding proteins were used. Treatment of C3Heb/FeJ mice with 100 micrograms/kg… CONTINUE READING