Neutrophil gelatinase-associated lipocalin (NGAL): a new piece of the anemia puzzle?

  title={Neutrophil gelatinase-associated lipocalin (NGAL): a new piece of the anemia puzzle?},
  author={Davide Bolignano and Giuseppe Coppolino and Valentina Donato and Antonio Lacquaniti and Caterina Bono and Michele Buemi},
  journal={Medical science monitor : international medical journal of experimental and clinical research},
  volume={16 6},
Neutrophil Gelatinase-Associated Lipocalin (NGAL), a small 25-kD peptide, originally discovered as an antibacterial factor of natural immunity and an acute-phase protein, represents a key factor in the regulation of erythrocyte growth due to its ability to inhibit the maturation and differentiation of bone marrow erythroid precursors. When a condition of primary anemia occurs, the body has a double response with respect to NGAL production and its systemic effects. Because NGAL is a protective… CONTINUE READING


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