Neutrophil gelatinase-associated lipocalin: a new antioxidant that exerts its cytoprotective effect independent on Heme Oxygenase-1.

@article{Roudkenar2011NeutrophilGL,
  title={Neutrophil gelatinase-associated lipocalin: a new antioxidant that exerts its cytoprotective effect independent on Heme Oxygenase-1.},
  author={Mehryar Habibi Roudkenar and Raheleh Halabian and Parisa Bahmani and Amaneh Mohammadi Roushandeh and Yoshikazu Kuwahara and Manabu Fukumoto},
  journal={Free radical research},
  year={2011},
  volume={45 7},
  pages={810-9}
}
Neutrophil Gelatinase-Associated Lipocalin (NGAL/Lcn2), a member of the lipocalin family, has a variety of functions. There are extensive studies examining the expression of NGAL under harmful conditions. However, its precise function remains poorly understood. Heme Oxygenase 1 (HO-1) is an enzyme with well-established cytoprotective effects. Previous work showed that NGAL induces expression of HO-1. Interestingly, the same stimuli induced the expression of both NGAL and HO-1. The current study… CONTINUE READING
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