Neutrophil gelatinase-associated lipocalin: a biomarker in COPD.

  title={Neutrophil gelatinase-associated lipocalin: a biomarker in COPD.},
  author={Tomas Mikal Eagan and Jan Kristian Dam{\aa}s and Thor Ueland and Marianne Voll-Aanerud and Tom Eirik Mollnes and Jon Andrew Hardie and Per S. Bakke and P{\aa}l Aukrust},
  volume={138 4},
BACKGROUND Neutrophil gelatinase-associated lipocalin (NGAL) is an antimicrobial peptide that could be involved in the pathogenesis of COPD. This study aimed to measure the plasma levels of NGAL in a large cohort of patients with COPD and control subjects and examine the levels of NGAL by COPD characteristics. METHODS The study included 402 patients with COPD and 229 control subjects aged 40 to 76 years from the Bergen COPD Cohort Study. All patients with COPD had an FEV(1)/FVC ratio of < 0.7… CONTINUE READING


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