Neutrophil function and metabolism in individuals with diabetes mellitus.

  title={Neutrophil function and metabolism in individuals with diabetes mellitus.},
  author={Tatiane C Alba-Loureiro and Carolina D Munhoz and Joilson Oliveira Martins and Giselle Cerchiaro and Cristoforo Scavone and R. A. Curi and Paulina Sannomiya},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  volume={40 8},
Neutrophils act as first-line-of-defense cells and the reduction of their functional activity contributes to the high susceptibility to and severity of infections in diabetes mellitus. Clinical investigations in diabetic patients and experimental studies in diabetic rats and mice clearly demonstrated consistent defects of neutrophil chemotactic, phagocytic and microbicidal activities. Other alterations that have been reported to occur during inflammation in diabetes mellitus include: decreased… CONTINUE READING


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Down-regulation of mast cell activation and airway reactivity in diabetic rats: role of insulin

  • SC Cavalher-Machado, WT de Lima, AS Damazo, V de Frias Carvalho, MA Martins, PM Silva
  • Eur Respir J
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