Neutrophil extracellular traps contribute to the pathogenesis of acid-aspiration-induced ALI/ARDS

@inproceedings{Li2018NeutrophilET,
  title={Neutrophil extracellular traps contribute to the pathogenesis of acid-aspiration-induced ALI/ARDS},
  author={Haitao Li and Xiaoting Zhou and Hongyi Tan and Yongbin Hu and Lemeng Zhang and Shuai Liu and Minhui Dai and Yi Xiao Li and Qian Li and Zhi Mao and Pinhua Pan and Xiaoli Su and Chengpin Hu},
  booktitle={Oncotarget},
  year={2018}
}
Background Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a manifestation of systemic inflammation in the lungs, but the factors that trigger inflammation in ALI/ARDS are unclear. We hypothesized that neutrophil extracellular traps (NETs) contribute to the pathogenesis of acid aspiration-induced ALI/ARDS. Results Analysis of bronchial aspirates from ARDS patients showed that NETs were significantly correlated with the degree of ARDS (r = -0.5846, p = 0.0359). NETs in… CONTINUE READING