Neutrophil adherence induced by lipopolysaccharide in vitro. Role of plasma component interaction with lipopolysaccharide.

@article{Worthen1992NeutrophilAI,
  title={Neutrophil adherence induced by lipopolysaccharide in vitro. Role of plasma component interaction with lipopolysaccharide.},
  author={George Scott Worthen and Natalie J. Avdi and S W Vukajlovich and Peter S. Tobias},
  journal={The Journal of clinical investigation},
  year={1992},
  volume={90 6},
  pages={2526-35}
}
Endotoxemia results in neutrophil localization within a number of microcirculatory beds, reflecting in part an adhesive interaction between neutrophils and the vascular endothelial cell. In previous studies, endotoxin or lipopolysaccharide (LPS) treatment of rabbits resulted in neutrophil sequestration at LPS concentrations well below those effective at increasing neutrophil adherence in vitro. We hypothesized that LPS-induced neutrophil adherence involved a plasma component. In the absence of… CONTINUE READING
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