Neutrophil activation and arteritis induced by C. albicans water-soluble mannoprotein-beta-glucan complex (CAWS).

@article{IshidaOkawara2007NeutrophilAA,
  title={Neutrophil activation and arteritis induced by C. albicans water-soluble mannoprotein-beta-glucan complex (CAWS).},
  author={Akiko Ishida-Okawara and Noriko Nagi-Miura and Toshiaki Oharaseki and Kei Takahashi and Akinori Okumura and Hitoshi Tachikawa and Shin-ichiro Kashiwamura and Haruki Okamura and Naohito Ohno and Hidechika Okada and Peter A Ward and Kazuo Suzuki},
  journal={Experimental and molecular pathology},
  year={2007},
  volume={82 2},
  pages={220-6}
}
We have established a mouse model which shows the symptoms of coronary arteritis after consecutive injections of CAWS, which is released from Candida albicans. In this study, we examined neutrophil activation in the initial period after CAWS injection intraperitoneally. During 10 min to 16 h after the injection, blood profiles and neutrophil functions were determined. At the same time, levels of inflammatory cytokines and chemokines in plasma were measured. Furthermore, level of ICAM-1 as a… CONTINUE READING

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