Neutrophil accumulation promotes intimal hyperplasia after photochemically induced arterial injury in mice.

@article{Shimazawa2005NeutrophilAP,
  title={Neutrophil accumulation promotes intimal hyperplasia after photochemically induced arterial injury in mice.},
  author={Masamitsu Shimazawa and Shinji Watanabe and Kazunao Kondo and Hideaki Hara and Mitsuyoshi Nakashima and Kazuo Umemura},
  journal={European journal of pharmacology},
  year={2005},
  volume={520 1-3},
  pages={156-63}
}
The role of leukocytes in the pathogenesis of coronary arterial disease has become a focus for clinical research. The aim of this study was to determine whether neutrophil accumulation would participate in the development of intimal hyperplasia after endothelial injury in mice, and whether d-myo-inositol hexakisphosphate (phytic acid) which inhibits the binding of L- and P-selectin to sialyl Lewis(X) could inhibit the development of intimal hyperplasia. Endothelial injury was inflicted in one… CONTINUE READING

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