Neutrophil Gelatinase B and Chemokines in Leukocytosis and Stem Cell Mobilization

@article{Starckx2002NeutrophilGB,
  title={Neutrophil Gelatinase B and Chemokines in Leukocytosis and Stem Cell Mobilization},
  author={Sofie Starckx and Philippe E. Van den Steen and Anja Wuyts and Jo Van Damme and Ghislain Opdenakker},
  journal={Leukemia \& Lymphoma},
  year={2002},
  volume={43},
  pages={233 - 241}
}
Leukocytosis is a physiopathological mechanism primarily to combat infections, whereas stem cell mobilization is induced for therapeutical purposes. Both processes are dependent on the balance between leukocyte and stem cell retention and mobilization. The retention is mediated by the specific architecture of the bone marrow, adhesion molecules and the production of chemokines in the bone marrow, which attract escaped immature cells to the marrow. Mobilization is the effect of the action of… 
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  • 2002
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