Neutropenia associated with cloxacillin and other semisynthetic penicillins in children.

Abstract

Five children treated with high dose of semisynthetic penicillin for three to four weeks developed neutropenia (<1.5 x 10(9)/L). All patients were on cloxacillin. In addition, three patients received ampicillin, and one received piperacillin therapy for the same duration. All patients developed neutropenia 15 to 23 days following therapy and resolved 8 to… (More)

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