Neutropenia and impaired neutrophil migration in type IB glycogen storage disease.

@article{Beaudet1980NeutropeniaAI,
  title={Neutropenia and impaired neutrophil migration in type IB glycogen storage disease.},
  author={Arthur L Beaudet and Donald C. Anderson and Virginia V. Michels and William J. Arion and Alex J. Lange},
  journal={The Journal of pediatrics},
  year={1980},
  volume={97 6},
  pages={
          906-10
        }
}
The association of neutropenia with type IB glycogen storage disease was observed in siblings. Biochemical studies of liver demonstrated a defect in glucose-6-phosphate transport. Neutrophil mobilization in vivo was impaired but the bone marrow was normal histologically. In vitro studies of neutrophils indicated a defect in random and directed cell migration. The studies suggest that a role for glucose-6-phosphate transport in neutrophils should be considered. 

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 50 extracted citations

Glycogen storage disease type Ib

European Journal of Pediatrics • 1983
View 7 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…