Neutron energy-dependent initial DNA damage and chromosomal exchange.

  title={Neutron energy-dependent initial DNA damage and chromosomal exchange.},
  author={Kenichi Tanaka and N. Gajendiran and Satoru Endo and Kenshi Komatsu and Masaharu Hoshi and Nanao Kamada},
  journal={Journal of radiation research},
  volume={40 Suppl},
This study was undertaken to investigate the biological effect of monoenergetic neutrons on human lymphocyte DNA and chromosomes. Monoenergetic neutrons of 2.3, 1.0, 0.79, 0.57, 0.37 and 0.186 MeV were generated, and 252Cf neutrons and 60Co gamma-rays were also used for comparison. Biological effect was evaluated two ways. The RBE values with the comet assay were estimated as 6.3 and 5.4 at 0.37 MeV and 0.57 MeV relative to that of 60Co gamma-rays, and chromosome aberration rates were also… CONTINUE READING