Neutralizing monoclonal antibodies to human immunodeficiency virus type 1 do not inhibit viral transcytosis through mucosal epithelial cells.

@article{Chomont2008NeutralizingMA,
  title={Neutralizing monoclonal antibodies to human immunodeficiency virus type 1 do not inhibit viral transcytosis through mucosal epithelial cells.},
  author={Nicolas Chomont and Hakim Hocini and Jean-Chrysostome Gody and Hicham Bouhlal and Pierre Becquart and Corinne Krief-Bouillet and Michel Daniel Kazatchkine and Laurent B{\'e}lec},
  journal={Virology},
  year={2008},
  volume={370 2},
  pages={246-54}
}
HIV-1 transcytosis has been proposed as a potential mechanism allowing the virus to cross the epithelium during mucosal transmission. Epitopes of the HIV-1 envelope involved in this process have not been identified yet. Here, we assessed a large panel of HIV neutralizing antibodies recognizing well-characterized epitopes of the HIV-1 envelope for their… CONTINUE READING