Neutralizing epitopes specific for influenza B virus Yamagata group strains are in the 'loop'.

@article{Nakagawa2003NeutralizingES,
  title={Neutralizing epitopes specific for influenza B virus Yamagata group strains are in the 'loop'.},
  author={Naoko Nakagawa and Ritsuko Kubota and Toshimasa Nakagawa and Yoshinobu Okuno},
  journal={The Journal of general virology},
  year={2003},
  volume={84 Pt 4},
  pages={769-73}
}
To study the neutralizing epitopes of influenza B virus Yamagata group strains, two monoclonal antibodies (mAbs) were used to select escape mutants of the virus. mAbs 5H4 and 3A12 were found to react with B/Yamagata group strains in haemagglutination inhibition and neutralization tests; no reactivity with B/Victoria group strains was observed. Most of the mutants reacted poorly to polyclonal ferret antibody against the 1998 isolate. Analysis of the deduced amino acid sequences identified a… CONTINUE READING
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