Neutralizing-antibody-combining (NAC) test for measuring antigenic potency of poliomyelitis vaccine.


An in vitro test for the quantitative determination of the antigenic potency of poliomyelitis vaccine is described. This test-termed the neutralizing-antibody-combining (NAC) test-is based on the measurement of the capacity of an inactivated virus in tissue culture to bind neutralizing antibody. Details of the experimental design and technique are given… (More)


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