Neutralizing activity of saliva against cytomegalovirus.

@article{Saccoccio2011NeutralizingAO,
  title={Neutralizing activity of saliva against cytomegalovirus.},
  author={Frances M. Saccoccio and M Kate Gallagher and Stuart P. Adler and Michael A. McVoy},
  journal={Clinical and vaccine immunology : CVI},
  year={2011},
  volume={18 9},
  pages={1536-42}
}
Congenital cytomegalovirus (CMV) disease is the leading cause of permanent disability in neonates in the United States. Neutralizing antibodies in saliva may protect against maternal CMV infection by blocking viral entry into oral epithelial cells, but the antibody response to CMV in the saliva following natural infection is not well characterized. Saliva specimens from naturally infected individuals were tested for CMV-neutralizing activity using epithelial and fibroblast cells. Saliva from… CONTINUE READING

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