Neutralization of poliovirus by cell receptors expressed in insect cells.

@article{Kaplan1990NeutralizationOP,
  title={Neutralization of poliovirus by cell receptors expressed in insect cells.},
  author={Gilla Kaplan and Marion S Freistadt and Vincent R. Racaniello},
  journal={Journal of virology},
  year={1990},
  volume={64 10},
  pages={4697-702}
}
To examine the interaction of the poliovirus receptor (PVR) with virus and the role of the PVR in virus entry, the PVR was expressed in insect cells. Poliovirus bound to insect cells infected with a recombinant baculovirus (AcPVR) carrying cDNA encoding the PVR. Antibodies raised against PVR expressed in bacteria immunoprecipitated a 67-kilodalton… CONTINUE READING