Neutralization of a clade B primary isolate by sera from human immunodeficiency virus-uninfected recipients of candidate AIDS vaccines.

@article{ZollaPazner1997NeutralizationOA,
  title={Neutralization of a clade B primary isolate by sera from human immunodeficiency virus-uninfected recipients of candidate AIDS vaccines.},
  author={Susan Zolla-Pazner and Carl R. Alving and Robert B. Belshe and Phillip M. Berman and Sherri T Burda and P. Chigurupati and Mary Lou Clements and A. M. Duliege and J. L. Excler and C Hioe and James R. Kahn and M Juliana McElrath and Sharpe Sharpe and Faruk Sinangil and K Steimer and Mary Clare Walker and Nadia Wassef and Songjuan Xu},
  journal={The Journal of infectious diseases},
  year={1997},
  volume={175 4},
  pages={
          764-74
        }
}
The inability of antibodies induced by experimental human immunodeficiency virus type 1 (HIV-1) vaccines to neutralize HIV-1 primary isolates may be due to a failure to elicit such antibodies, antigenic differences between the vaccine and the strains tested, insensitivity of the assays used, or to a combination of factors. New neutralization assays were used to determine the ability of candidate AIDS vaccines to generate neutralizing antibodies for clade B primary isolate BZ167, which is… CONTINUE READING

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