Neutralization of Latrodectus mactans and L. hesperus Venom by Redback Spider (L. hasseltii) Antivenom

@article{Daly2001NeutralizationOL,
  title={Neutralization of Latrodectus mactans and L. hesperus Venom by Redback Spider (L. hasseltii) Antivenom},
  author={F. Daly and R. Hill and G. Bogdan and R. Dart},
  journal={Journal of Toxicology: Clinical Toxicology},
  year={2001},
  volume={39},
  pages={119 - 123}
}
  • F. Daly, F. Daly, +2 authors R. Dart
  • Published 2001
  • Biology, Medicine
  • Journal of Toxicology: Clinical Toxicology
Objective: To test the effectiveness of L. hasseltii (redback spider) antivenom in neutralizing the lethal effects of L. hesperus and L. mactans(North American black widow) venoms. Methods: LD50 values for the L. hesperus and L. mactans venom preparations were determined. A prospective, randomized, double-blind antivenom efficacy experiment was then performed for each venom using a mouse envenomation model. The following treatments were premixed and incubated at 25°C for 1 hour prior to… Expand
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