Neutralization of HPV16, 18, 31, and 58 pseudovirions with antisera induced by immunizing rabbits with synthetic peptides representing segments of the HPV16 minor capsid protein L2 surface region.

@article{Kondo2007NeutralizationOH,
  title={Neutralization of HPV16, 18, 31, and 58 pseudovirions with antisera induced by immunizing rabbits with synthetic peptides representing segments of the HPV16 minor capsid protein L2 surface region.},
  author={Kazunari Kondo and Yoshiyuki Ishii and Hiroyuki Ochi and Tamae Matsumoto and Hiroyuki Yoshikawa and Tadahito Kanda},
  journal={Virology},
  year={2007},
  volume={358 2},
  pages={266-72}
}
Neutralizing antibody against human papillomavirus (HPV) minor capsid protein L2 can cross-neutralize different HPV genotypes in vitro. To identify the segments containing the cross-neutralization epitopes of HPV16 L2, we characterized antisera obtained by immunizing two rabbits with each of the ten synthetic peptides of 14 to 20 amino acids (aa) long, which represents a part of the HPV16 L2 sequence from aa 14 to 144. The antisera against the peptides within the region from aa 18 to 144… CONTINUE READING