Neutralization Assay for Zika and Dengue Viruses by Use of Real-Time-PCR-Based Endpoint Assessment.

@article{Wilson2017NeutralizationAF,
  title={Neutralization Assay for Zika and Dengue Viruses by Use of Real-Time-PCR-Based Endpoint Assessment.},
  author={Heather L Wilson and Thomas H. Tran and Julian D. Druce and Myrielle Dupont-Rouzeyrol and Michael G. Catton},
  journal={Journal of clinical microbiology},
  year={2017},
  volume={55 10},
  pages={
          3104-3112
        }
}
The global spread and infective complications of Zika virus (ZKV) and dengue virus (DENV) have made them flaviviruses of public health concern. Serological diagnosis can be challenging due to antibody cross-reactivity, particularly in secondary flavivirus infections or when there is a history of flavivirus vaccination. The virus neutralization assay is considered to be the most specific assay for measurement of anti-flavivirus antibodies. This study describes an assay where the neutralization… CONTINUE READING