Neutralizacion de los efectos locales del veneno de Bothrops asper por un antiveneno polivalente

@article{Gutirrez1981NeutralizacionDL,
  title={Neutralizacion de los efectos locales del veneno de Bothrops asper por un antiveneno polivalente},
  author={Jos{\'e} Mar{\'i}a Guti{\'e}rrez and Fernando Chaves and Ronald Eduardo D{\'i}az Bola{\~n}os and Luis Cerdas and Ermila Rojas and Olga P{\'e}rez Arroyo and Edgardo Villamil Portilla},
  journal={Toxicon},
  year={1981},
  volume={19},
  pages={493-500}
}
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104 Citations
Highly Influential Citations
3
Background Citations
20
Methods Citations
4
Results Citations
2

104 Citations

Citation Type

Citation Type

Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom.
Intramuscular administration of antivenoms in experimental envenomation by Bothrops asper: comparison between Fab and IgG.
Neutralization of Thalassophryne nattereri (niquim) fish venom by an experimental antivenom.
Neutralization of myonecrosis, hemorrhage, and edema induced by Bothrops asper snake venom by homologous and heterologous pre-existing antibodies in mice.
  • A. Rucavado, B. Lomonte
  • Biology, Medicine
    Toxicon : official journal of the International Society on Toxinology
  • 1996
Comparative study on the ability of IgG and Fab sheep antivenoms to neutralize local hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom.
Inhibition of toxic activities of Bothrops asper venom and other crotalid snake venoms by a novel neutralizing mixture.
TLDR
This work suggests that the polyvalent antivenom used in Central America could be enriched with a B. asper serum fraction producing a more effective antivenome, and local application of CaNa2 EDTA to neutralize hemorrhagic toxins, immediately after a snake bite, may provide rapid inhibition of local damage caused by the venoms.
Heparin-antivenom association: differential neutralization effectiveness in Bothrops atrox and Bothrops erythromelas envenoming.
TLDR
It was verified that heparin, in doses of 3 and 6 IU, was not effective in neutralizing the desfibrinating and edema-forming activities of B. atrox venom and the hemorrhagic and coagulant actions of both venoms.
Neutralization of local effects of the terciopelo (Bothrops asper) venom by blood serum of the colubrid snake Clelia clelia.
Neutralization of crotaline snake venoms from Central and South America by antivenoms produced in Brazil and Costa Rica.
Production of monovalent anti-Bothrops asper antivenom: development of immune response in horses and neutralizing ability.
TLDR
It is proposed that monovalent antivenom may be highly effective in the case of envenomations induced by Bothrops asper venom; its use in treating accidents by L. muta and C. durissus would be indicated only if polyvalent antikenom is not available.
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References

SHOWING 1-10 OF 14 REFERENCES
Mionecrosis, hemorragia y edema inducidos por el veneno de Bothrops asper en ratón blanco
Efectos proteolitico, hemorragico y mionecrotico de los venenos de serpientes costarricenses de los generos Bothrops, Crotalus y Lachesis☆
Effectiveness of antivenin (Crotalidae) polyvalent following injection of Crotalus venom.
Antivenin for the treatment of local tissue damage due to envenomation by Southeast Asian snakes. Ineffectiveness in the prevention of local tissue damage in mice after envenomation.
  • M. Homma, A. Tu
  • Medicine
    The American journal of tropical medicine and hygiene
  • 1970
Abstract Antivenins currently used in Southeast Asia to treat snake-bite were administered to mice to determine their effectiveness in the prevention of local tissue damage after envenomation.…
Polyvalent antivenin in treatment of experimental snake venom poisoning.
  • S. Minton
  • Biology
    The American journal of tropical medicine and hygiene
  • 1954
TLDR
Intraperitoneal injection of antivenin gave slightly better results than local infiltration of the injured tissue, but Antivenin does not prevent local tissue necrosis under these circumstances.
Hemorrhagic toxins from rattlesnake (Crotalus atrox) venom. Pathogenesis of hemorrhage induced by three purified toxins.
TLDR
The experimental injection of three purified hemorrhagic toxins induced hemorrhage by the same mechanism as does the crude venom, ie, per rhexis, in addition, one of the toxins, hemorrhagic toxin beta, causes myonecrosis.
THE SURGICAL TREATMENT OF SNAKE BITES
Toxicologic study of snake venoms from Costa Rica.
Isolation of myotoxic component from rattlesnake (Crotalus viridis viridis) venom. Electron microscopic analysis of muscle damage.
TLDR
The pathogenesis of myonecrosis induced by a purified component of rattlesnake (Crotalus viridis viridis) venom was studied at the light and electron microscopic levels, with the pure component altered skeletal muscle cells specifically, withThe sarcoplasmic reticulum being the primary site of action.
Hemorrhagic, myonecrotic, thrombotic and proteolytic activities of viper venoms.
  • A. Tu, M. Homma, B. Hong
  • Biology
    Toxicon : official journal of the International Society on Toxinology
  • 1969
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