Neutralización de las actividades tóxicas y enzimáticas de cuatro venenos de serpientes de Guatemala y Honduras por el antiveneno polivalente producido en Costa Rica

@article{Rojas1987NeutralizacinDL,
  title={Neutralizaci{\'o}n de las actividades t{\'o}xicas y enzim{\'a}ticas de cuatro venenos de serpientes de Guatemala y Honduras por el antiveneno polivalente producido en Costa Rica},
  author={Gustavo Rojas and Jos{\'e} Mar{\'i}a Guti{\'e}rrez and Jos{\'e}A. Gen{\'e} and Maribel G{\'o}mez and Luis Cerdas},
  journal={Revista De Biologia Tropical},
  year={1987},
  volume={35},
  pages={59-67}
}
We studied the ability of the polyvalent antivenom produced in Costa Rica to neutralize lethal, hemorrhagic, edema-forming, proteolytic, hemolytic, hyaluronidase and fibrinolytic activities of the venoms of Bothrops asper and B. nummifer from Honduras, and of Agkistrodon bilineatus and Crotalus durissus durissus from Guatemala. Neutralizing ability of antivenom was expressed as ED50 (effective dose 50%), defined as the antivenom/venom ratio at which the activity of the venom is reduced 50… 
The venom of Bothrops asper from Guatemala: toxic activities and neutralization by antivenoms.
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The evaluation of the ability of a polyspecific antivenom manufactured in Costa Rica to recognize the proteins of Atropoides mexicanus and A. picadoi venoms revealed the low immunogenicity of a number of venom components (PLA2s, CRISPs, P-I SVMPs, and some serine proteinases), underscoring the need to search for innovative immunization protocols to improve the immune response to these antigens.
Venom of Bothrops asper from Mexico and Costa Rica: intraspecific variation and cross-neutralization by antivenoms.
Toxinological Characterization of the Whole Venom of the Rattlesnake Crotalus durissus cumanensis (Viperidae) from Porshoure, Venezuelan Guajira
The whole venom of the rattlesnake Crotalus durissus cumanensis (Viperidae) from Porshoure, Venezuelan Guajira, was characterized toxinologically in this research, determining: lethal dose 50 (LD50),
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