Neutral sulfate berberine modulates cytokine secretion and increases survival in endotoxemic mice


AbstractAim:Berberine is thought to be an immunomodulator, so the present study aimed to investigate the effect of berberine on mortality, lung and intestine injury in endotoxemic mice, and the mechanism of its action.Methods:Mice were challenged with lipopolysaccharide (LPS, 28 mg/kg, ip), and neutral sulfate berberine was administrated intragastrically… (More)
DOI: 10.1111/j.1745-7254.2006.00368.x


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