Neutral genomic regions refine models of recent rapid human population growth.

  title={Neutral genomic regions refine models of recent rapid human population growth.},
  author={Elodie Gazave and Li Ma and Diana Chang and A. F. Coventry and Feng Gao and Donna M. Muzny and Eric Boerwinkle and Richard A. Gibbs and Charles F. Sing and Andrew G. Clark and Alon Keinan},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={111 2},
Human populations have experienced dramatic growth since the Neolithic revolution. Recent studies that sequenced a very large number of individuals observed an extreme excess of rare variants and provided clear evidence of recent rapid growth in effective population size, although estimates have varied greatly among studies. All these studies were based on protein-coding genes, in which variants are also impacted by natural selection. In this study, we introduce targeted sequencing data for… CONTINUE READING
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