Neurotrophins and psychiatric disorders.

  title={Neurotrophins and psychiatric disorders.},
  author={Eero Castr{\'e}n},
  journal={Handbook of experimental pharmacology},
Increasing number of studies has during the last decade linked neurotrophic factors with the pathophysiology of neuropsychiatric disorders and with the mechanisms of action of drugs used for the treatment of these disorders. In particular, brain-derived neurotrophic factor BDNF and its receptor TrkB have been connected with the pathophysiology in mood disorders, and there is strong evidence that BDNF signaling is critically involved in the recovery from depression with both pharmacological and… CONTINUE READING


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