Neurotrophins and asthma: novel insight into neuroimmune interaction.

@article{Nockher2006NeurotrophinsAA,
  title={Neurotrophins and asthma: novel insight into neuroimmune interaction.},
  author={Wolfgang Andreas Nockher and Harald Renz},
  journal={The Journal of allergy and clinical immunology},
  year={2006},
  volume={117 1},
  pages={
          67-71
        }
}
There is increasing evidence that neuronal dysfunction and dysregulation contribute to the pathogenesis of allergic asthma. Many functional aspects of peripheral neurons strongly depend on the activity of neurotrophins, a family of mediators originally defined by their neuronal growth activity. More recently, it has been discovered that neurotrophins (eg, nerve growth factor, brain-derived neurotrophin factor, and neurotrophin 3) have profound activities on various immune cells involved in the… CONTINUE READING
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