Neurotrophin signalling: novel insights into mechanisms and pathophysiology.

@article{Mitre2016NeurotrophinSN,
  title={Neurotrophin signalling: novel insights into mechanisms and pathophysiology.},
  author={Mariela Mitre and Abigail Mariga and Moses V. Chao},
  journal={Clinical science},
  year={2016},
  volume={131 1},
  pages={
          13-23
        }
}
  • Mariela Mitre, Abigail Mariga, Moses V. Chao
  • Published in Clinical science 2016
  • Medicine
  • Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are prominent regulators of neuronal survival, growth and differentiation during development. While trophic factors are viewed as well-understood but not innovative molecules, there are many lines of evidence indicating that BDNF plays an important role in the pathophysiology of many neurodegenerative disorders, depression, anxiety and other psychiatric disorders. In particular, lower levels of BDNF are associated with the… CONTINUE READING

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