Neurotrophin activates signal transduction in oligodendroglial cells: expression of functional TrkC receptor isoforms.

@article{Kumar1996NeurotrophinAS,
  title={Neurotrophin activates signal transduction in oligodendroglial cells: expression of functional TrkC receptor isoforms.},
  author={Shalini Sree Kumar and Jean de Vellis},
  journal={Journal of neuroscience research},
  year={1996},
  volume={44 5},
  pages={490-8}
}
The role of the NT-3 has been implicated in the survival of progenitor oligodendrocytes in culture. The object of this study was to investigate the expression of the TrkC receptor and its responsiveness in glial cells. We report the expression of two TrkC receptor isoforms in rat primary oligodendrocyte cultures, a glial progenitor cell line, CG-4, and in C6 glioma cells. The reverse transcription-polymerase chain reaction-aided amplification of glial trkC with specific primers from the kinase… CONTINUE READING
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