Neurotrophin-3 (NT-3) modulates early differentiation of oligodendrocytes in rat brain cortical cultures.

Multiple extracellular signals are required for oligodendroglia survival, proliferation and differentiation, and increasing evidence has accumulated that also neurotrophins regulate glial cell development in the central nervous system (CNS). In the present study we have investigated the influence of neurotrophin-3 (NT-3) on the in vitro differentiation and… (More)