Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia.

@article{Lai2013NeurotrophicPO,
  title={Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia.},
  author={Puei-Lene Lai and Murali Naidu and Vikineswary Sabaratnam and Kah-Hui Wong and Rosie Pamela David and Umah Rani Kuppusamy and Noorlidah Abdullah and Sri Nurestri Abd Malek},
  journal={International journal of medicinal mushrooms},
  year={2013},
  volume={15 6},
  pages={
          539-54
        }
}
Neurotrophic factors are important in promoting the growth and differentiation of neurons. Nerve growth factor (NGF) is essential for the maintenance of the basal forebrain cholinergic system. Hericenones and erinacines isolated from the medicinal mushroom Hericium erinaceus can induce NGF synthesis in nerve cells. In this study, we evaluated the synergistic interaction between H. erinaceus aqueous extract and exogenous NGF on the neurite outgrowth stimulation of neuroblastoma-glioma cell NG108… 

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