Neurotrophic factors and neurologic disease.


Discovered only 40 years ago, nerve growth factor is the prototypic neurotrophic factor. By binding to specific receptors on certain neurons in the peripheral nervous system and brain, nerve growth factor acts to enhance their survival, differentiation, and maintenance. In recent years, many additional neurotrophic factors have been discovered; some are… (More)


Cite this paper

@article{Holtzman1994NeurotrophicFA, title={Neurotrophic factors and neurologic disease.}, author={David M Holtzman and William C. Mobley}, journal={The Western journal of medicine}, year={1994}, volume={161 3}, pages={246-54} }