Neurotrophic and neurorescue effects of Echinacoside in the subacute MPTP mouse model of Parkinson's disease.

@article{Zhao2010NeurotrophicAN,
  title={Neurotrophic and neurorescue effects of Echinacoside in the subacute MPTP mouse model of Parkinson's disease.},
  author={Qing Zhao and Junpeng Gao and Wenwei Li and Dingfang Cai},
  journal={Brain research},
  year={2010},
  volume={1346},
  pages={224-36}
}
Many experiments support the notion that augmentation of neurotrophic factors' (NTFs) activity, especially glial cell line-derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor (BDNF) could prevent or halt the progress of neurodegeneration in Parkinson's disease (PD). However, application of NTFs as therapeutic agents for PD is hampered by the difficulty in delivering them to specific brain regions safely and effectively. Another potential strategy is to stimulate the… CONTINUE READING

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