Neurotrophic activity of monomeric glucophosphoisomerase was blocked by human immunodeficiency virus (HIV‐1) and peptides from HIV‐1 envelope glycoprotein

  title={Neurotrophic activity of monomeric glucophosphoisomerase was blocked by human immunodeficiency virus (HIV‐1) and peptides from HIV‐1 envelope glycoprotein},
  author={Yaffa Mizrachi},
  journal={Journal of Neuroscience Research},
  • Y. Mizrachi
  • Published 1 June 1989
  • Biology, Chemistry
  • Journal of Neuroscience Research
Glucophosphoisomerase (GPI), a glycolytic enzyme, was recently described to share 90% sequence homology with neuroleukin, a recently discovered growth factor which promotes motor neuron regeneration in vivo, survival of peripheral and central neurons in vitro, and affects B cell immunoglobulin synthesis. 
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