Neurotrophic actions of a novel molluscan epidermal growth factor.

@article{Hermann2000NeurotrophicAO,
  title={Neurotrophic actions of a novel molluscan epidermal growth factor.},
  author={Petra M. Hermann and Ronald E van Kesteren and Willem C Wildering and Sherry D. Painter and J. Michael Reno and Jennifer S. Smith and S T Bharani Kumar and Wijnand P. M. Geraerts and Lowell H. Ericsson and August B. Smit and Andrew Bulloch and Gregg T. Nagle},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2000},
  volume={20 17},
  pages={
          6355-64
        }
}
The mammalian epidermal growth factor (EGF) is expressed in the developing and adult CNS, and it has been implicated in the control of cell proliferation, differentiation, and neurotrophic events. Despite extensive evolutionary conservation of the EGF motif in a range of different types of proteins, secreted EGF homologs with neurotrophic actions have not been reported in invertebrates. In this study, we present a novel member of the family of EGF-like growth factors, an EGF homolog from the… CONTINUE READING

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