Neurotrophic Keratopathy: Therapeutic Approach Using a Novel Matrix Regenerating Agent.

@article{Guerra2017NeurotrophicKT,
  title={Neurotrophic Keratopathy: Therapeutic Approach Using a Novel Matrix Regenerating Agent.},
  author={Marta Gomes Guerra and Sara Homem de Melo Marques and Jo{\~a}o Quadrado Gil and Joana Campos and Paula Cristina Rodrigues dos Ramos and Andreia de Faria Martins Rosa and Maria Joao C Quadrado and J. N. Murta},
  journal={Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics},
  year={2017},
  volume={33 9},
  pages={662-669}
}
PURPOSE To evaluate the efficacy and tolerance of a new matrix-regenerating agent (RGTA), Cacicol®, a polymer that mimics heparan sulfates bound to extracellular matrix proteins, avoiding its proteolysis, to treat neurotrophic keratopathy (NK). METHODS Uncontrolled prospective clinical study performed between January 2014 and May 2016. Twenty-five… CONTINUE READING