Neurotransplantation of the Biological Clock in Mammals, Importance and Perspectives

@inproceedings{Boer1997NeurotransplantationOT,
  title={Neurotransplantation of the Biological Clock in Mammals, Importance and Perspectives},
  author={Gerard J. Boer},
  year={1997}
}
The tool of neurotransplantation has been successfully introduced in the chronobiology of mammals. Grafting of the foetal suprachiasmatic nucleus (SCN) in the IIIrd ventricle of the brain of SCN-lesioned arhythmic rodents restored free-running circadian activity patterns. This ultimately proves the SCN to be the central circadian pacemaker system. However, recovery is not seen in all animals with a surviving SCN implant and the rhythm is usually not as robust as seen for the intact system… CONTINUE READING