Neurotransplantation of magnetically labeled oligodendrocyte progenitors: magnetic resonance tracking of cell migration and myelination.

@article{Bulte1999NeurotransplantationOM,
  title={Neurotransplantation of magnetically labeled oligodendrocyte progenitors: magnetic resonance tracking of cell migration and myelination.},
  author={Jeff W M Bulte and S. C. Zhang and Peter van Gelderen and V{\'i}t Herynek and Elaine Kay Jordan and Ian D. Duncan and Joseph A. Frank},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1999},
  volume={96 26},
  pages={15256-61}
}
Demyelination is a common pathological finding in human neurological diseases and frequently persists as a result of failure of endogenous repair. Transplanted oligodendrocytes and their precursor cells can (re)myelinate axons, raising the possibility of therapeutic intervention. The migratory capacity of transplanted cells is of key importance in determining the extent of (re)myelination and can, at present, be evaluated only by using invasive and irreversible procedures. We have exploited the… CONTINUE READING
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