Neurotransmitters and suicidal behavior. The evidence from cerebrospinal fluid studies.

@article{sberg1997NeurotransmittersAS,
  title={Neurotransmitters and suicidal behavior. The evidence from cerebrospinal fluid studies.},
  author={Marie {\AA}sberg},
  journal={Annals of the New York Academy of Sciences},
  year={1997},
  volume={836},
  pages={158-81}
}
  • Marie Åsberg
  • Published 1997 in Annals of the New York Academy of Sciences
Studies of neurotransmitter metabolites in cerebrospinal fluid (CSF) were initially focused on depressive illness. Although several studies have demonstrated low concentrations of the serotonin metabolite, 5-hydroxyindoleacetic acid (5-HIAA), and the dopamine metabolite, homovanillic acid (HVA), in depressed patients, these early studies may have been biased by concomitant administration of antidepressant drugs (which tend to lower CSF 5-HIAA), amount of CSF drawn (there is a concentration… CONTINUE READING

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