Neurotransmitters and neuromodulators during early human development.

@article{Herlenius2001NeurotransmittersAN,
  title={Neurotransmitters and neuromodulators during early human development.},
  author={Eric Herlenius and Hugo Lagercrantz},
  journal={Early human development},
  year={2001},
  volume={65 1},
  pages={21-37}
}
BACKGROUND Neurotransmitters such as monoamines appear in the embryo before the neurones are differentiated. They may have other functions than neurotransmission during embryogenesis such as differentiation and neuronal growth. For example, serotonin may act as a morphogen. A number of neuropeptides are expressed during ontogenesis, but their function has been difficult to establish. Maybe some of them remain as evolutionary residues. Fast-switching neurotransmitters like the excitatory amino… CONTINUE READING
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