Neurotransmission in Parkinson's disease: beyond dopamine.

  title={Neurotransmission in Parkinson's disease: beyond dopamine.},
  author={Paolo Barone},
  journal={European journal of neurology},
  volume={17 3},
Parkinson's disease (PD) is most frequently associated with characteristic motor symptoms that are known to arise with degeneration of dopaminergic neurons. However, patients with this disease also experience a multitude of non-motor symptoms, such as sleep disturbances, fatigue, apathy, anxiety, depression, cognitive impairment, dementia, olfactory dysfunction, pain, sweating and constipation, some of which can be at least as debilitating as the movement disorders and have a major impact on… CONTINUE READING


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