Neurotransmission: The second sensor

The expression of the language-associated gene sushi repeat-containing X-linked 2 (SRPX2) is repressed by the transcription factor FOXP2. Here, SRPX2 knockdown led to a decrease in excitatory cortical synaptic density and impaired ultrasonic vocalizations in mouse pups. Modulating FOXP2 levels also regulated synaptic density by controlling SRPX2 expression… CONTINUE READING