Neurotoxin-based models of Parkinson's disease.

@article{Bov2012NeurotoxinbasedMO,
  title={Neurotoxin-based models of Parkinson's disease.},
  author={Jordi Bov{\'e} and Christian Perier},
  journal={Neuroscience},
  year={2012},
  volume={211},
  pages={51-76}
}
Animal experimentation in the Parkinson's disease (PD) field is a classic example of how the use of animal models to study diseases can have a significant impact on human health. Among the different neurotoxin-based animal models of PD that are presently available, the 6-hydroxydopamine (6-OHDA) and the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) models have been established and validated as useful models for the development of therapeutic strategies aimed to treat motor symptoms and to… CONTINUE READING
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