Neurotoxin A2NTX blocks fast inhibitory and excitatory transmitter release from presynaptic terminals.

Abstract

Our recent study showed a possibility that newly developed A2 type botulinum toxin (A2NTX) inhibits both spontaneous and evoked transmitter release from inhibitory (glycinergic or GABAergic) and excitatory (glutamatergic) nerve terminals using rat spinal sacral dorsal commissural nucleus neurons. In the present study, to determine the modulatory effect of… (More)

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Cite this paper

@article{Yamaga2012NeurotoxinAB, title={Neurotoxin A2NTX blocks fast inhibitory and excitatory transmitter release from presynaptic terminals.}, author={Toshitaka Yamaga and Shuji Aou and Min-Chul Shin and Masahito Wakita and Norio Akaike}, journal={Journal of pharmacological sciences}, year={2012}, volume={118 1}, pages={75-81} }