Neurotoxicology of cannabis and THC: a review of chronic exposure studies in animals.

@article{Scallet1991NeurotoxicologyOC,
  title={Neurotoxicology of cannabis and THC: a review of chronic exposure studies in animals.},
  author={Andrew C. Scallet},
  journal={Pharmacology, biochemistry, and behavior},
  year={1991},
  volume={40 3},
  pages={671-6}
}
Several laboratories have reported that chronic exposure to delta-9-tetrahydrocannabinol (THC) or marijuana extracts persistently altered the structure and function of the rat hippocampus, a paleocortical brain region involved with learning and memory processes in both rats and humans. Certain choices must be made in designing experiments to evaluate cannabis neurotoxicity, such as dose, route of administration, duration of exposure, age at onset of exposure, species of subjects, whether or how… CONTINUE READING
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