Neurotoxicity of Diethylpropion

  title={Neurotoxicity of Diethylpropion},
  author={Sonia Galv{\'a}n-Arzate and Abel Santamar{\'i}a},
  journal={Annals of the New York Academy of Sciences},
Abstract: The effects of diethylpropion (DEP), an amphetamine derivative and a well‐known anorectic agent, on different neurochemical and behavioral markers of toxicity in rats were evaluated. Animals received a daily dose of DEP (5 mg/kg po) for 15 days, and all tests were performed 24 hours after the last DEP administration. As neurochemical markers, the brain regional levels of some amino acids, such as aspartate (Asp), glutamate (Glu), gamma‐aminobutyric acid (GABA), and glutamine (Gln), as… 
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