Neurotoxic esterase (NTE) assay: optimized conditions based on detergent-induced shifts in the phenol/4-aminoantipyrine chromophore spectrum.

Abstract

An assay for neurotoxic esterase (neuropathy target esterase, NTE) was developed by Johnson (1,2) to assess the delayed neurotoxic potential of organophosphorus compounds. NTE activity is calculated from the rate of phenyl valerate hydrolysis resistant to paraoxon and sensitive to mipafox inhibition under specified conditions of inhibitor concentrations, pH… (More)

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Cite this paper

@article{Kayyali1991NeurotoxicE, title={Neurotoxic esterase (NTE) assay: optimized conditions based on detergent-induced shifts in the phenol/4-aminoantipyrine chromophore spectrum.}, author={Usamah S. Kayyali and Theodore B. Moore and Jeffrey C. Randall and Rudy J. Richardson}, journal={Journal of analytical toxicology}, year={1991}, volume={15 2}, pages={86-9} }