Neurotoxic characteristics of spatial recognition damage of the hippocampus in mice following subchronic peroral exposure to TiO2 nanoparticles.

@article{Ze2014NeurotoxicCO,
  title={Neurotoxic characteristics of spatial recognition damage of the hippocampus in mice following subchronic peroral exposure to TiO2 nanoparticles.},
  author={Yuguan Ze and Lei Sheng and Xiaoyang Zhao and Xiao Ze and Xuecen Wang and Qiuping Zhou and Jialiang Liu and Yifei Yuan and Suxin Gui and Xuezi Sang and Qingqing Sun and J. Z. Hong and Xiaohong Yu and Ling Wang and Bingyan Li and Fashui Hong},
  journal={Journal of hazardous materials},
  year={2014},
  volume={264},
  pages={219-29}
}
Due to the increased application of titanium dioxide nanoparticles (TiO2 NPs) in various areas, numerous studies have been conducted which have confirmed that exposure to TiO2 NPs may result in neurological damage in both mice and rats. However, very few studies have focused on the molecular mechanisms of spatial recognition injury. In the present study, to understand the possible neurobiological responses of the mouse hippocampus following subchronic peroral exposure to low level TiO2 NPs… CONTINUE READING

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